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amalian

amalian is a range of mono-phasic and bi-phasic hyaluronic acid based dermal fillers manufactured in Germany by S&V (Skin & Vision) Technologies and distributed in the UK by 4T Medical. The current product range includes 9 CE mark filler products to target indications for rejuvenation by the treatment of fine lines and wrinkles and deep folds to strong volume augmentation or lip augmentation.

S & V Technologies have been manufacturing implantable medical products for the past 20 years and has entered the dermal filler market with a range of very high quality products based on a its new patented technology called Core-in-shell (CIS) which they claim ensures long term stability of the product in the skin, as well as an easy application through the needle or cannula due to the of the gel.

The product range includes two distinct sub brands for the mono-phasic and bi-phasic lines, LT for the mono-phasic soft cross-linked acid and expert for the bi-phasic product using the CIS technology of highly cross-linked hyaluronic acid micro-particles inside a non-cross-linked hyaluronic acid shell.

Non-animal hyaluronic acid

Mono-phasic range (LT)
The mono-phasic hyaluronic acid fillers (amalian LT smoothline, amalian I LT active, amalian II LT intense and amalian LT beauty lips) are homogenous gels of soft cross-linked acid. Each formulation of LT has been individually customised for the indication of use and are generally suited for treating fine to moderate wrinkles and folds or for lip enhancement and augmentation.

The concentration of hyaluronic acid and cross-linking of each gel is tuned to target an optimal viscoelastic status for the according to the manufacturer, as well as a very smooth injection flow.

amalian balance is the non-cross linked product in the mono-phasic line.

Bi-phasic range (expert)
The amalian expert gel is a highly cross-linked hyaluronic acid which is formulated with their CIS technology.

This unique CIS technology makes amalian from other products made of cross-linked hyaluronic acid. The "Core-in-Shell" structure forms a stable core of highly cross-linked hyaluronic acid surrounded by long chains of non-cross-linked hyaluronic acid, which form a protective shell. This structure delays the degradation of hyaluronic acid by hyaluronidase (found naturally in the body which metabolises hyaluronic acid over time) and helps to prolong the effects of the treatment.

Due to their specific properties, all amalian expert gels have to be injected in smaller volumes and deeper than traditional hyaluronic acid products.

The CIS technology has a effect on what is known as the viscoelasticity of the gel. When no pressure is applied to it, the gel is (thick) and thus able to augment where it is placed. When pressure is applied as it is injected into the skin it will under the pressure which make the injection smooth and product delivery easy. Then, once injected, the hyaluronic acid gel will immediately "bounce back" into its original thick, viscous state to act as a filler within the dermal tissues.

The amalian LT products can be used on top of the expert if additional correction and treatment is needed more superficially, so a combination treatment may be suggested.

No allergy test required.

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European CE marked medical device.

Trained medical professionals only. 

In the mono-phasic (LT) range there are 5 different formulations available:

amalian balance - 12 mg/ml, non-cross-linked HA (32G)

Hyaluronic acid gel for improving skin hydration.

It is specially developed for rejuvenation, bio revitalising and hydration of face, décolleté, neck and hands using a mesotherapy technique into the upper (superficial) dermis.

It is to repeat treatments three times at intervals.

Touch-up treatments should be performed every four to six months for long lasting skin rejuvenation.

amalian LT smoothline - 8 mg/ml, HA (30G)

Soft cross-linked hyaluronic acid gel designed to smooth age related fine lines, vertical lip lines, crow’s feet, lines, perioral lines (around the mouth), border of the lips and glabella.

Tear can also be lifted.

The gel is injected in the upper to middle layer of skin.

For tear troughs subcutaneous injections are placed outside the orbital area.

amalian I LT active - 16 mg/ml, cross-linked HA

This mono-phasic soft cross-linked hyaluronic acid gel is well suited to correcting fine to medium lines and soft wrinkles in the forehead, and periorbital areas (around the eyes, crow’s feet etc.), as well as for lip and lip enhancement and is injected into the upper to middle layer of the skin.

amalian II LT intense - 24 mg/ml, cross-linked HA

This mono-phasic soft hyaluronic acid gel is designed to lift middle to deep wrinkles and folds.

The formulation is most suited for lifting nasolabial folds, oral commissures and marionette lines, smoothing skin depressions (e.g. acne scars) and moderate reshaping of facial contours such as the chin or non-surgical nose reshaping, e.g. bridge augmentation, as well as stronger lip augmentation treatments.

It is injected into the deep dermis, thus should not be used in the forehead or the glabella.

amalian LT beauty lips - 22 mg/ml, cross-linked HA

amalian LT beauty lips is a new mono-phasic soft gel designed to satisfy the needs of lips tissue.

This extra smooth gel was formulated to lips fullness and contours.

For achieving beautiful and natural looking lips, the manufacturers recommend placing five tiny gel spots in the lips symmetrically, followed by gentle modelling after injection.

In the bi-phasic range there are 4 different formulations available:

amalian I expert premium - 8,4 mg/ml, highly cross-linked HA

This bi-phasic highly cross-linked acid gel is for filling fine to medium wrinkles and is injected into the middle layer of the skin (upper to mid dermis).

Due to the CIS technology amalian I expert premium lasts up to 12 months, but has to be injectedto start with in lower doses and in deeper layers of the dermis, compared to the I LT active product to achieve the long-lasting effect.

amalian II expert effect - 24 mg/ml HA

This bi-phasic highly hyaluronic acid gel (for use by experienced users) is suitable for medium to deep wrinkles and folds, for acne scars and the vermilion border of the lips.

This gel has to be injected into the middle to deep dermis and claims to require less material than any other hyaluronic acid gels to achieve a long-lasting effect.

III expert volume - 24 mg/ml, cross-linked HA

gel designed to restore age related facial volume loss (lipoatrophy) and contours.

This formulation is used for cheek and chin augmentation, deep folds and scars and for re-contouring of the jawline, as well as so called